Research Associate – Reagent Development – Protein Biochemistry

Job Description
About the Role

We are seeking an outstanding Research Associate to join the New Product Development team to support the development and commercial launch of new products. This is a unique cross-disciplinary position that will work closely with a variety of groups including Molecular Biology, Chemistry, Microfluidics, QC, and Manufacturing, to develop and validate novel reagents for the rapid expansion of 10x product lines. Candidates should have a solid understanding of protein expression and purification in Ecoli or other heterologous expression systems. Previous experience with refolding and purification of recombinant protein complexes or protein and antibody conjugation and purification is highly desirable. The successful applicant will have exceptional attention to detail and the ability to meticulously execute complex experiments.

Individuals applying for this position must be self-starters, strategic thinkers, action driven, flexible in changing direction and methods, thrive in a fast-paced environment, excel at managing multiple priorities, succeed in communicating with all levels within the organization and provide immediate contribution.

What You Will Be Doing

Hands on in the production, purification, and quality control of proteins and protein conjugates.
Minimum Requirements

Bachelor’s degree in Biology, Biochemistry, or related field with industry experience in recombinant protein production or protein conjugation and purification.
Experience with protein characterization including SDS PAGE, Western Blot, FPLC, Mass Spectrometry, UV-VIS, and fluorometric analysis
Hands-on experience with protein purification (using affinity and traditional chromatographic techniques) on AKTA chromatography purification workflows or similar.
Basic understanding of antibody characterization and immunology
Strong collaboration and communication skills
Preferred Skills / Experience

Purification of recombinant expressed proteins
Experience with in vitro refolding, purification, characterization, and scale-up production of proteins from E. coli inclusion bodies.
Experience in GMP, GLP setting and good documentation practices preferred.
Experience operating liquid handling robots and other laboratory automation tools. Experience programming these instruments would be highly beneficial.

About 10x Genomics

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.

We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference.

Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law.

10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.

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