Principal Investigator (PI) – Small Molecule

  • Full Time
  • San Diego
  • Posted 1 month ago
  • $120k to $135k USD / YEAR
  • Salary: $120k to $135k
  • Must be able to work in the US

BioAgilytix – San Diego (MicroConstants)


Principal Investigator (PI) – San Diego
BioAgilytix San Diego, 9050 Camino Santa Fe, San Diego, California, United States of America 

At BioAgilytix, we are passionate about premier science and the impact it has on our world. Our team of highly experienced scientists and professionals deliver tailored services for supporting new medicine breakthroughs with best-in-class bioanalytical services. We are tirelessly committed to our customers by being solution-oriented and deadline-driven. . . and we are growing. Our culture is fast-paced, fun and never boring. Because we work across numerous clients and drug modalities, your career can develop rapidly. You’ll gain experience with a variety of challenges all while you enable life-changing, life-saving therapeutics to the patients that need them. 

In this role, you will apply your real-world, expert insight to help our customers successfully navigate the complexities of small or large molecule bioanalysis. This role is the singular scientific expert and main contact for our clients through every stage of the project lifecycle. You are also a teacher, mentor and coach to the BioAgilytix project team providing day-to-day leadership both in and out of the lab. Our clients trust us to deliver accurate and reliable results, and this role provides the critical project leadership and continuity they expect. Our clients depend on us to provide solutions, on time and on budget, as a result of their continued relationships with our BPMs and quality of the team’s work.

We are looking for candidates who have proven and deep scientific experience paired with demonstrated leadership presence. Our best candidates are people who have a passion for learning and teaching, with the patience and listening skills to appeal to the perspectives and interests of others. If you are able to balance confidence with humility while driving quality and efficient projects, then you’ll be right at home here at BioAgilytix.


Design and oversee the execution of development, validation, and sample analysis of biologics, proteins, peptides, small molecules, and/or biomarkers, using various techniques including chromatographic (LC/MS), cell-based, immunogenicity, immunoassays, and/or enzymatic assays for support of preclinical, clinical and product release studies
Partner closely with clients to ensure successful on time execution of deliverables
Manage and lead the team (scientists, analysts, and study coordinators) supporting client solutions, modeling collaboration and teamwork



Ability to establish, maintain and deepen working relationships through strong written and spoken communication
Ability to consult with a long-term perspective in addressing customers’ (both internal and external) needs and issues with an intent to strengthen their business
Thorough knowledge of industry best practices of experimental planning and design
Experience working in GxP environments and demonstrated knowledge of GxP regulations
Advanced capabilities in data analysis and data visualization statistical analysis
Demonstrated experience serving in a people management role and leading teams; exhibit active interest in coaching, mentoring, and inspiring others to do their best work and drive results

Competencies and Qualifications Preferred

Bachelor’s degree in chemistry, molecular biology, biochemistry, immunology, biotechnology, or related field with not less than ten (10) years’ experience in a scientific laboratory environment; or Master’s or PhD. with equivalent experience
Ability to develop cell-based and/or immuno- assays in some or all of the following platforms:
Immunoassay: ELISA, MSD-ECL, RIA, DELFIA, HTRF, and AlphaScreen
Cell-based: Cell reporter assays, cell viability assays, cell second messenger assays
Ability to develop chromatographic assays including LC/MS by extracting analytes of interest from complex biological matrices using protein precipitation, liquid-liquid, solid phase, immunoprecipitation or other extraction technique
Medical Insurance (HDHP with HSA; PPO)
Dental Insurance
Vision Insurance
Flexible Spending Account (medical; dependent care)
Short Term Disability | Long Term Disability
Life Insurance
Paid Time Off (4 weeks per year)
Paid Holidays (9 scheduled; 3 floating)
401k with Employer Match
Employee Referral Program (up to $10k)
Free Coffee, Tea, Fruit, and Snacks
Discounted Vending Machines (25 cents for everything!)
Team Wellness Challenges/Events

BioAgilytix provides equal employment opportunities to all employees and applicants for employment without regard to race, color, ancestry, national origin, gender, sexual orientation, marital status, religion, age, disability, gender identity, results of genetic testing, service in the military, or any other group protected by federal, state, or local law.

Tagged as: bioanalysis, biochemistry, biology, chemistry, lcms, management

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