As a result of exciting developments both with Caribou’s internal pipeline programs and with our external partnership, we have multiple early-stage projects at Caribou focused on the preclinical discovery and development of CAR-T cell therapy candidates. We are looking for an independent, goal-oriented Scientist to help us propel this work forward. In this exciting and challenging role, you will support early stage preclinical programs using genome editing technologies, T cell biology and immunology to develop novel CAR T cell therapies. The ideal motivated and enthusiastic candidate will join a highly dynamic and collaborative environment, working cross-functionally with multiple researchers on cutting-edge technologies to deliver on impactful research projects that we believe will ultimately positively impact the lives of patients.
Working with a matrixed team to develop and advance preclinical allogeneic CAR-T cell programs targeting liquid and/or solid tumors
Developing and troubleshooting in vitro functional assays for the characterization of allogeneic CAR-T cell therapy candidates
Designing, coordinating, and executing in vitro and ex vivo immunology experiments
Analyzing/interpreting data and communicating the results clearly and promptly
Keeping detailed, organized, and accurate records of experiments and results
Staying current on primary literature
PhD in immunology, molecular biology, cell biology, or a closely related field with 0-3 years of post doc
Experience in planning and executing in vitro functional assays to characterize primary immune cells including, but not limited to, cytotoxicity assays, cytokine/chemokine measurements, and proliferation assessment
Experience in multi-parameter flow cytometry and data analysis
Ability to work independently and as part of a team
Excellent interpersonal, verbal, and written communication skills are essential in our collaborative research environment
Work in pharmaceutical or biotechnology company focused on immuno-oncology
Primary cell culture
Experience evaluating therapeutic candidates in animal models
Experience writing technical reports
Understanding of regulatory guidelines for cell therapies
Caribou compensation and benefits include:
Comprehensive compensation package, which includes stock options and an employee stock purchase program for all employees
Generous paid vacation time, in addition to company-observed holidays and floating holidays
Excellent medical, dental, and vision insurance
401(k) retirement savings plan, which includes matching employer contributions
Tuition reimbursement program
Caribou is an equal opportunity employer and does not discriminate based on race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law. In addition, Caribou prohibits the harassment of any individual on any of the bases listed above or any other characteristics protected under federal, state, or local laws. Legal authorization to work in the United States is required. In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire.
Caribou requires employees to be fully vaccinated, including a booster shot, against COVID-19 unless they have an approved medical or religious accommodation. Proof of such vaccination will be required as part of the hiring process.
For more information about Caribou, visit www.cariboubio.com and follow the company @CaribouBio.