Senior Associate Scientist, Tumor Biology (non-PhD)

Pfizer Inc

Hope Changes Lives

Why Patients Need You  
Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.  


What You Will Achieve
We seek an accomplished Sr. Associate Scientist to join the in vivo Tumor Biology Translational Sciences group within Oncology Research & Development (ORD), La Jolla, California. The successful candidate will join a dynamic team of scientists, playing a leading role in the characterization of models of cancer and evaluating new drug candidates. Participate in pre-clinical drug discovery and development projects with a focus on targeted therapeutics, epigenetics and the tumor microenvironment. Characterize and develop small molecules in close collaboration with partner lines as an integral member of drug discovery teams. Evaluating anti-tumor effects of single agents or in combination with other modalities, employing and developing new cutting-edge in vivo cancer models and providing technical and scientific expertise in in vivo pharmacology to enable target identification, validation, prioritization, and efficient drug discovery of small molecules in Tumor Biology. 


Ideal applicants will have excellent communication and organizational skills, critical problem-solving abilities, and a commitment to excellence.


How You Will Achieve It
Assist/Conduct in vivo studies to evaluate and establish efficacy, PK/PD relationship, combination strategy, biomarker identification and analysis.
Interpretation, presentation and documentation of experiments.
Presentation of results within a multidisciplinary team environment.
Regularly read scientific papers and implement learnings in the study designs or project strategies. 


BS in Cancer Biology, Immunology or equivalent experience in a related discipline with 3 years of laboratory work experience in academia or industry or MS with relevant laboratory experience
Ability to follow novel scientific or technological developments, and to implement them in the laboratory.
In vivo skills (IV, PO dosing), blood/tissue collections
Experience with in vivo models
Excellent written and oral communication and presentation skills.
Strong ability to multi-task and work productively in a fast-paced, highly collaborative, and diverse team environment
Capability to contribute to a vivid and challenging intellectual environment
Ability to integrate biological concepts into experimental design


Ex vivo skills such as Western blot and qPCR
Experience with GraphPad Prism and/or Studylog

Lifting, sitting, standing, walking, bending, ability to perform mathematical calculations
Must be able to wear specialized protective clothing and PPE (lab coat, safety shoes/glasses/etc).


Must be willing and able to work after hours as needed to ensure study integrity

Other Job Details

Work Location Assignment: On Premise. On Premise colleagues work in a Pfizer site because it’s needed to get their job done. They may have flexibility to work remotely from time to time, but they are primarily on-site.

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