• Full Time
  • Anywhere
  • Posted 1 month ago

Scripps Research

Scripps Research is ranked the most influential institution in the world for its impact on innovation. We expand basic knowledge in the biosciences, and use these fundamental advancements to develop profound innovations that improve wellbeing. Our educational and training programs mold talented and committed students and postdocs into leading edge scientists.  Scientists in the institute’s five academic research departments work hand-in-hand with researchers of the Scripps Research Translational Institute and Calibr to merge foundational studies in biology, chemistry and computer science with translational science to produce pioneering drugs and advances in digital and precision medicine. Together, we cultivate new scientific leaders and expand the frontiers of knowledge to deliver medical breakthroughs to better human health around the globe. If you have a passion for making a difference, this could be your opportunity to join our transformative team. The Balch lab is at the forefront of exciting new developments of genetic disease therapeutics.

 Position Title:  Staff Scientist

 Position Summary:

The genomics-oriented cell biology laboratory of Dr. William Balch in the Department of Molecular Medicine at Scripps Research in San Diego, CA  has an opening for  a Staff Scientist to perform and guide laboratory efforts. The Balch laboratory is interested in understanding and treating the underlying basis of mono- and polygenic diseases impacting the protein fold in response to genetic variation in the human population. Candidates will contribute to the development and application of novel experimental/computational approaches to assess the impact of genetic variation and the protein folding machinery on genetic diversity for different gene targets affecting liver, lung, and neurodegenerative disease. For examples of current efforts see recent publications (

Skillsets of interest include proven expertise in tissue culture, biochemical tools (SDS-PAGE, immunoblotting, ELISA, etc.), cell biological tools including imaging, and a working knowledge of molecular techniques including generation of mutant plasmids, transfection with plasmids/siRNA for transient protein expression in cell-based reporter systems. Knowledge of higher throughput assay formats (96/384 well) as well as computational tools including machine learning/bioinformatics are considered a plus. Contact:


Ph.D. in relevant scientific discipline. A minimum of 2 years postdoctoral experience.

​Physical Requirements:

This position works in an office environment. Further details of the physical requirements of established essential functions for this position will be addressed/discussed during the interview process.

 Location: La Jolla, California 

 Compensation: The expected hiring range for this position is $64,480 to $90,272 per year, commensurate with experience. Consideration will be given to experience that exceeds the listed requirements.

 The above statements describe the level of work performed and expected in general terms.  The statements are not intended to list all the responsibilities, duties and/or skills required of employees so classified, and the content herein is subject to change due to the business needs of Scripps Research, with or without notice.   Furthermore, nothing in this job description shall be interpreted to be in conflict with or to eliminate or modify in any way the employment-at-will status of Scripps Research staff. 

EEO Statement:
The Scripps Research Institute is an Equal Opportunity Employer. We promote diversity of thought, culture and background in the fields of science. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status. Underrepresented individuals are encouraged to apply.

COVID-19 update:

The safety and well-being of our candidates, our people and their families continues to be a top priority. Until restrictions change, interviews will be conducted virtually.



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