Staff Scientist-Super-Resolution Microscopy

The Scripps Research Institute HR – CA

The Scripps Research Institute HR - CA

ABOUT US: Scripps Research is ranked the most influential institution in the world for its impact on innovation. We expand basic knowledge in the biosciences, and use these fundamental advancements to develop profound innovations that improve wellbeing. Our educational and training programs mold talented and committed students and postdocs into leading edge scientists. Scientists in the institute’s five academic research departments work hand-in-hand with researchers of the Scripps Research Translational Institute and Calibr to merge foundational studies in biology, chemistry and computer science with translational science to produce pioneering drugs and advances in digital and precision medicine. Together, we cultivate new scientific leaders and expand the frontiers of knowledge to deliver medical breakthroughs to better human health around the globe. If you have a passion for making a difference, this could be your opportunity to join our transformative team.
 
Position Title: Staff Scientist-Super-Resolution Microscopy
 
Position Summary:
 The Staff Scientist will assist the Core Director with the operations of a state-of-the-art, multi-user Microscopy Laboratory at The Scripps Research Institute and will report to the Microscopy Core Director.
 
Duties and Responsibilities:
Assist with operations of super-resolution microscopy systems, including a newly installed MINFLUX system.
Undertake projects or tasks related to super-resolution microscopy.
Provide training on the operation of the super-resolution microscopes to TSRI scientists, faculty and staff.
Maintain the microscopes and associated equipment, troubleshooting problems and assuring instrument integrity by arranging for service or by providing solutions. Oversee operation of super-resolution microscopes and maintenance of ancillary equipment, including QC, validation, and day-to- day operation.
Arrange for equipment service as needed.
Undertake sample preparation for super-resolution microscopy.
Assist users, and/or provide user training in areas of MINFLUX microscope operation, specimen preparation, imaging, analysis and documentation. Provide necessary quality-controlled protocols and reagents for direct use in applications or for user applications as needed.
Maintain a current understanding of “state-of-the-art” knowledge in the SR fields.
Maintain all records relevant to instrument usage, maintenance, material and reagent use, chemical stocks and other inventories.
Coordinate with Microscopy Core staff to administer correlative microscopy applications utilizing LM and EM.
Assist with billing for services on schedule as required by the financial system.
 
​Physical Requirements: This position works in a laboratory environment. Further details of the physical requirements of established essential functions for this position will be addressed/discussed during the interview process.
 
Requirements: 
Ph.D. in a life science field, such as cell biology, developmental biology, biochemistry, biophysics or similar.
Experience with advanced photonics.
Minimum of 3 years of experience working with super-resolution microscopy (especially STORM).
Working knowledge of design, theory and operation of advanced light microscopy systems, including skill and experience in their operation.
Experience with biological experimental design and implementation.
Ability to troubleshoot when problems arise and determine course of action for maintenance and service.
Experience training others in advanced microscopy systems and techniques.
Experience in digital image acquisition and preparation, including familiarity with image analysis software such as Fiji/ImageJ, Imaris, Image Pro, etc.
Experience with Microsoft Word, Excel, PowerPoint and other software.
Knowledge of safety protocols and standard operating procedures need ed to carry out all job responsibilities in a safe manner in order to protect oneself and those around them, minimizing or eliminating exposure to hazardous materials and/or conditions.
Demonstrated organizational skills and technical problem solving skills. The individual must be able to organize electronic data, information and images as well as laboratory equipment (microscopes, sample preparation, etc.).
Ability to effectively organize their time, and that of others, to accommodate user needs and be responsive to the user base in both a timely and equitable manner.
Excellent written and verbal communication, especially in developing experimental approaches in collaboration with PI’s.
Ability to communicate with a diverse array of people from a wide variety of cultural and educational backgrounds, both individually and in groups.
 Location: La Jolla, California 
 
Compensation: Salary commensurate with experience.
 
EEO Statement: Scripps is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
 
COVID-19 update: The safety and well-being of our candidates, our people and their families continues to be a top priority. Until restrictions change, interviews will be conducted virtually. New hires will work remotely, unless specifically authorized for campus access.

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