Research Associate, Cell Biology

ViaCyte is a leading regenerative medicine company harnessing the latest innovations in science, engineering and regenerative medicine to develop functional cures for chronic diseases.  Our proprietary stem cell-based therapy approach has possible application across multiple disease states that can potentially be treated by replacing lost or malfunctioning cells or proteins.  The dedicated team at ViaCyte is initially focused on treating Type 1 diabetes with a proprietary platform designed to differentiate stem cells into cells that function like a pancreas by automatically controlling blood glucose levels.  

Backed by two decades of research and expertise, we are the first to advance this approach into human clinical trials and show therapeutic effect in patients with the most advanced cell replacement portfolio for Type 1 diabetes.  Through partnerships with two world class leaders, CRISPR Therapeutics and W L. Gore & Associates, we are optimizing our cells and therapeutic delivery to create cell replacement therapies for diabetes that do not require immunosuppression and represent a functional cure.  With collaboration and patient focus driving our work, our mission is to reduce the relentless burden of disease management, improve health outcomes, and enhance quality of life for people living with chronic diseases.

ViaCyte is headquartered in San Diego, California. For more information, please visit www.viacyte.com and connect with ViaCyte on Twitter, Facebook, and LinkedIn.

Position Description:

You are a highly motivated and talented contributor and looking to join an exciting and fast-growing company to develop cell therapeutics and product platforms. You will have research experience in the development of differentiation protocols for stem cell derived cell therapies. Under moderate supervision, you shall utilize techniques in cell culture and cell & molecular biology to contribute to the overall research and development of gene-edited cell therapeutics. You demonstrate the ability to dissect challenging problems, interact effectively with team members, and manage multiple priorities in-parallel.

You are available full-time for a position located in San Diego, CA. The position will be 100% on-site and requires flexibility in working schedule to accommodate weekend work when necessary.

Essential Duties & Responsibilities:

  • Grow, passage, and differentiate human pluripotent stem cells using aseptic technique and multiple small-scale manufacturing platforms. Adjust the differentiation protocol to optimize the cellular product.
  • Analyze the progression of cell differentiation in vitro through real time gene expression using Nanostring platform and other assays.
  • Execute, and interpret experiments, with a high degree of reliability.
  • Conduct own experimental troubleshooting on routine problems.
  • Perform basic statistical analysis of experimental data, where appropriate.
  • Prepare protocols and written study reports.
  • Survey relevant scientific literature to maintain awareness of issues and trends within the field.
  • Present studies effectively at internal group, department, or project team research meetings.
  • Highly self-motivated and flexibility in working schedule to accommodate weekend work when necessary.
  • Flexibility to handle rapidly changing objectives and timelines is essential.

Required Qualifications:

  • A bachelor’s degree in cell biology or a related field, and a minimum of two years of laboratory experience is required.
  • Equivalent combination of education and experience sufficient to successfully perform the job duties as listed above is acceptable.

Skills/Knowledge/Abilities:

  • Pluripotent stem cell culture and differentiation using aseptic techniques is required.
  • Knowledge of stem cell biology and/or developmental biology is preferred.
  • Experience with gene-editing using CRISPR/Cas9 in human pluripotent stem cells is an asset.
  • Experience with molecular biology techniques especially flow cytometry, RNA extraction, Nanostring, viability, cell death assays and ELISA is preferred.
  • Must have demonstrated the ability and willingness to perform a wide variety of tasks – from those which are routine in nature to those which require independent thought and analysis.
  • Detail-oriented, organized, strong time management skills with the capacity to meet deadlines.
  • Must be skilled in the Windows operating system and Microsoft Office, primarily Word, Excel and PowerPoint.
  • Strong verbal and written communication skills are required.

ViaCyte is committed to creating a diverse environment and is proud to be an Equal Opportunity Employer (EEO). All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status. Our programs are designed to comply with all applicable federal, state, and local laws, directives, and regulations, and cover all human resource actions including employment, compensation, benefits, training, education, promotions, and social/recreational programs.

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